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Kahmann L, Uciechowski P, Warmuth S, Plumakers B, Gressner AM, Malavolta M, et al

Beyond preventing deficiency, research suggests that higher therapeutic doses of methylcobalamin may actively support nerve repair and regeneration

Furthermore, while ashwagandhas ability to modulate the hypothalamic-pituitary-adrenal (HPA) axis may enhance stress resilience, it could theoretically disturb the delicate hormonal balance in patients with adrenal insufficiency, potentially worsening their condition [6]

These defects appear to get progressively worse with increasing age, and the oldest patients with COVID-19 had higher level of defects in these outcomes