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They reported 95% clearance of AN of axillae after seven sessions and concluded that long-pulsed alexandrite laser can effectively and safely treat acanthosis nigricans of the axillae.[11,27,36] Treatment of acanthosis nigricans maligna There is a case report of AMN regressing rapidly following treatment with cyproheptadine despite progression of metastatic disease

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Three of the six patients with severe disease died, while two showed severe neurodevelopmental impairment, and one case was not followed-up