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Supplements to Avoid (or Use With Caution) on GLP-1 Not all supplements are safe or beneficial alongside GLP-1 medications

These agonists directly activate the GLP-1R in hepatocytes and help alleviate hepatic steatosis through signaling pathways and genes involved in lipid metabolism

Semaglutide Weight Loss Results Semaglutide users can expect to lose between 15 and 20% after one year on the medication

Note: This handout should not be used as a substitute for medical advice from your health care team

How GLP-1s Work Mechanism: Mimic or enhance incretin hormones (GLP-1) to reduce appetite , slow gastric emptying , improve insulin secretion , and lower blood glucose