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IL-23 is indispensable in the survival, amplification and pathogenicity of Th17 cells in the late stage of Th17 differentiation[22].On the contrary, induced Treg (iTreg) cells is driven by high concentrations of TGF-, T-cell receptor (TCR) signaling and IL-2

doi: 10.1136/bmjnph-2020-000085 31 CallawayE.LedfordH

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