Only high doses (defined as greater than 30 mg/day), are associated with hypothyroidism and goiter, both of which rapidly normalize once administration of high doses is stopped 8,9,10 Even in people who have an underlying thyroid issue (such as autoimmune thyroiditis
But the top line results remain exciting.
Phentermine's sympathomimetic effects can cause: Tachycardia (elevated heart rate) Hypertension (raised blood pressure) Palpitations and arrhythmias Increased myocardial oxygen demand Whilst tirzepatide has shown improvements in cardiovascular risk factors in clinical trials, long-term cardiovascular outcome data are still emerging
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