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10 mg bottle $110 This peptide is used for the relief of osteoarthritis to stimulate cartilage synthesis and prevention of cartilage breakdown

Johnson JB, John S, Laub DR

The peptide also promotes polarization of macrophages from pro-inflammatory M1 phenotypes toward tissue-repairing M2 phenotypes, with treated macrophages showing 70% increased phagocytic activity for clearing inflammatory debris and 3-fold higher production of VEGF compared to untreated controls

This often causes pain in the legs and limits movement

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