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This leads to a natural decrease in calorie intake and, consequently, weight loss

It is contraindicated in people with T2D with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2

Given these drugs inhibit dopamine reception from foods, alcohol and other cravings it seems highly likely they will blunt other emotions too

For a side-by-side comparison of the two individual compounds, see: BPC-157 vs TB-500

Clinical trials demonstrated average weight reductions of 15-21% of body weight over 72 weeks in people with obesity (SURMOUNT-1), while more modest weight loss was observed in type 2 diabetes patients (SURPASS trials)