Implicated specifically were increased angiogenesis, elevated vascular endothelial growth factor (VEGF) levels, upregulation of the early growth response (egr-1) gene, enhanced nitric oxide (NO) and NO-synthase (eNOS) stimulation, and counteraction of increased free radical formation [1]
Topical Administration (Most Common) The most widely used approach is topical application via DMSO (dimethyl sulfoxide): Dissolve 3-5mg Dihexa in a few drops of DMSO Apply to forearm skin (DMSO acts as a carrier to drive the peptide through the skin) DMSO concentration: ~20-30% in the solution Pros: Effective absorption, avoids injection Cons: DMSO has a strong garlic-like odor that can transfer to breath/skin Starting Dose Begin at 1-3mg topically to assess response Work up to 3-5mg if tolerating well Cycling Protocol Dihexa appears to have lasting effects that persist after stopping likely due to synaptogenesis (new connections don't disappear when you stop)
(2014, November) This article highlights the promising therapeutic potential of BPC 157 in promoting tendon healing
We are told to keep the area clean, apply some over-the-counter ointment, and just wait
[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Vranes H., Knezevic T., Barisic I., Horvat Pavlov K., et al
