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To induce PCOS, the rats were administered dehydroepiandrosterone (DHEA) (Sigma, 6 mg/100 g body weight dissolved in 0.2 ml sesame oil) via subcutaneous injection for 21 consecutive days 24,53,54
Copper Transport and Bioavailability Copper is an essential cofactor for lysyl oxidase, superoxide dismutase, and several other enzymes critical to connective-tissue assembly and redox balance
When DPP 4 activity is inhibited, incretin hormones are protected from degradation, leading to increased insulin secretion and reduced glucagon release from pancreatic islet cells
By integrating HTS, in vitro, and in vivo methodologies, we aimed to unravel the complex genetic and molecular underpinnings of hair and nail biology, potentially leading to innovative treatments for various conditions related to these integumentary structures