Longevity varies by product and treatment area, but most dermal fillers last between 6 and 18 months before a touch-up is needed
Mild nausea, reduced appetite, feeling full quickly, and some fatigue are all normal first-week symptoms that don't require immediate medical attention
This study confirmed that tirzepatide induces a great improvement in insulin sensitivity compared to semaglutide, as already observed with HOMA-IR
Clinically, it is mainly used to treat T2DM and causes weight reduction when used in large doses (3mg/day) (83)
Administration of semaglutide at the dose regimen of ~ 90 g/kg/day failed to evidence significant weight loss but more importantly, led to alteration of cortical bone microarchitecture, represented by lower cortical thickness, and ultimately to a significant decrease in bone strength [69]