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Sun exposure and related skin damage, especially having a history of peeling or blistering sunburns, are the primary risk factors for melanoma

Melanotan II has demonstrated its ability to promote melanogenesis with minimal side effects

That does not mean never

Perkins says

Secondary outcomes The secondary outcomes are as follows: type 2 diabetes, glucose, HbA1c, insulin, lipid profile (LDL-cholesterol, HDL-cholesterol, triglycerides and apolipoprotein B), systolic blood pressure, diastolic blood pressure, and body mass index (BMI), which are well-established risk factors for CVD in clinical practice, or recently identified to be related to CVD in MR, such as apolipoprotein B [30, 31]