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Ischemic stroke was obtained from MEGASTROKE consortium (34,217 cases and 406,111 controls) [25], the UK Biobank (7961 cases and 384,003 controls), and Finngen Biobank (10,551 cases and 208,241 controls) [26]

rhamnosus not only induce an anti-inflammatory phenotype in M2 macrophages but also make M1 macrophages convert to a less inflammatory phenotype by suppressing the immune activation markers like CD14, CD80, and HLA-DR also decrease pro-inflammatory cytokines like IL-12, IL-1, and TNF- and increase anti-inflammatory cytokines like IL-10 and TGF- in SLE patient macrophages ( Figure 2 ) (101)

Glutathione is a powerful antioxidant naturally found in our body that plays a crucial role in skin health

Eur Rev Med Pharmacol Sci 25(18):58715875