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Many areas warrant further investigation, including the understanding of dopamine release in immune cells, examination of cell typespecific dopamine receptor signaling and specific immune activity, and delineation of dopamine-mediated inflammation from inflammation mediated by pharmacologic drugs that modify dopamine signaling

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The transition should include a washout period of at least 1-2 weeks after the last cagrilintide injection, followed by starting the retatrutide titration from the beginning (1 mg weekly)

10.1016/j.pneurobio.2013.11.006 175 LaloU.PalyginO.VerkhratskyA.GrantS