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Our efforts to devise treatments for cancer that work with the body instead of against it included biological response modifiers to stimulate immune response, ex vivo cultivation and anti-cancer antigen training of dendritic cells, tumor angiogenesis (blood vessel growth) inhibition, and the use of intravenous vitamin C (along with lipoic acid, in some cases) as a gentle anti-cancer agent and adjuvant

In turn, OS further activates the polyol pathway, increasing sorbitol in the body and preventing it from being metabolized properly, creating a vicious cycle (Singh et al., 2021)

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