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For employers that include GLP-1s for weight loss, this is expected to translate into higher overall cost exposure
239.) Available from: Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Homocysteine, Cleveland Clinic,
Semaglutide was the most cost-effective treatment compared to exenatide, dulaglutide, liraglutide, or no treatment in short-term analyses (approximately one and a half years) that assessed quality-adjusted life years and incremental cost-effectiveness ratios [135,136,137,138,139,140,141,142,143,144]
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The effect of oral semaglutide on cardiovascular outcomes was consistent with other clinical trials involving injectable semaglutide, but more trials are needed to determine if one method may be more effective than the other at reducing major cardiovascular events
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