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Early data from these registries has not shown a strong signal for major birth defects, but the numbers are still too small to be definitive

Therefore, the severe interstitial edema, more expressed in white than in gray mater, and severe neuron loss in hippocampal neurons, neurons of dentate nucleus, Purkinje cells and other cerebellar nuclei and less severe damage in the pons, the mesencephalon and lateral geniculate body could be a specific paracetamol effect and these territories could be involved in the occurrence of maximal paracetamol induced seizures

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