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JAMA psychiatry , 82 (1), 9498

Myth 2: Frag 176-191 and AOD 9604 are just as powerful as semaglutide. These fragments can help mobilize stubborn fat but do not produce the double-digit percentage weight losses of GLP-1 agonists

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As evidence has shown that IL-17 can increase depression and depression-like behaviors through the activation of microglia and inducing neuronal death, we can speculate that increased Th17 cells and IL-17A, induced by gut dysbiosis during the onset of GD are involved in the immune response of depression, exacerbating depressive symptoms